1 | library(data.table) |
| MyList | Gene Symbol | Description | Biological Process (GO) | Protein Function (Protein Atlas) | Subcellular Location (Protein Atlas) | Canonical Pathways | GO:0048812 neuron projection morphogenesi | GO:0043161 proteasome-mediated ubiquitin- | GO:1905114 cell surface receptor signalin | GO:0048589 developmental growth | GO:0000226 microtubule cytoskeleton organ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| <chr> | <chr> | <chr> | <chr> | <chr> | <chr> | <chr> | <int> | <int> | <int> | <int> | <int> |
| BCL11A | BCL11A | BAF chromatin remodeling complex subunit BCL11A | GO:1904799 regulation of neuron remodeling;GO:1904800 negative regulation of neuron remodeling;GO:2000173 negative regulation of branching morphogenesis of a nerve | Disease related genes; Predicted intracellular proteins; Transcription factors:Zinc-coordinating DNA-binding domains; Cancer-related genes:Candidate cancer biomarkers | Nucleoplasm (Supported); Additional: Nuclear bodies | 1 | 0 | 0 | 1 | 0 | |
| CELF4 | CELF4 | CUGBP Elav-like family member 4 | GO:1902866 regulation of retina development in camera-type eye;GO:0090394 negative regulation of excitatory postsynaptic potential;GO:0048025 negative regulation of mRNA splicing, via spliceosome | Predicted intracellular proteins | Nucleoplasm (Supported) | 1 | 0 | 1 | 0 | 0 | |
| CTNNB1 | CTNNB1 | catenin beta 1 | GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation;GO:1901963 regulation of cell proliferation involved in outflow tract morphogenesis;GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition | Cancer-related genes:Mutated cancer genes; Predicted intracellular proteins; Cancer-related genes:Mutational cancer driver genes; Disease related genes; Cancer-related genes:Candidate cancer biomarkers | Plasma membrane (Enhanced) | (M31)PID BETA CATENIN DEG PATHWAY; (M90)PID WNT CANONICAL PATHWAY; (M184)PID ECADHERIN KERATINOCYTE PATHWAY | 1 | 1 | 1 | 1 | 1 |
| DIP2A | DIP2A | disco interacting protein 2 homolog A | GO:0006085 acetyl-CoA biosynthetic process;GO:2000758 positive regulation of peptidyl-lysine acetylation;GO:0006084 acetyl-CoA metabolic process | Predicted intracellular proteins | Nucleoplasm (Approved) | 1 | 0 | 0 | 0 | 0 | |
| GIGYF1 | GIGYF1 | GRB10 interacting GYF protein 1 | Predicted intracellular proteins | Vesicles (Approved); Additional: Microtubules | 0 | 0 | 0 | 0 | 0 | ||
| KDM6B | KDM6B | lysine demethylase 6B | GO:0071557 histone H3-K27 demethylation;GO:0060992 response to fungicide;GO:0070076 histone lysine demethylation | Predicted intracellular proteins | Nuclear speckles (Approved) | 0 | 1 | 1 | 0 | 0 | |
| MBD5 | MBD5 | methyl-CpG binding domain protein 5 | GO:0060399 positive regulation of growth hormone receptor signaling pathway;GO:0060398 regulation of growth hormone receptor signaling pathway;GO:0060396 growth hormone receptor signaling pathway | Predicted intracellular proteins; Disease related genes | Midbody;Nucleoplasm (Supported) | 0 | 0 | 0 | 1 | 0 | |
| POGZ | POGZ | pogo transposable element derived with ZNF domain | GO:0051382 kinetochore assembly;GO:0051383 kinetochore organization;GO:0007064 mitotic sister chromatid cohesion | Predicted intracellular proteins; Transcription factors:Zinc-coordinating DNA-binding domains; Disease related genes | Nucleoplasm (Enhanced) | 0 | 1 | 0 | 0 | 0 | |
| PRPF4B | PRPF4B | pre-mRNA processing factor 4B | GO:0045292 mRNA cis splicing, via spliceosome;GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;GO:0000398 mRNA splicing, via spliceosome | Enzymes; Predicted intracellular proteins; Kinases:CMGC Ser/Thr protein kinases; ENZYME proteins:Transferases | Nuclear speckles (Supported) | 0 | 0 | 0 | 0 | 0 | |
| SLC16A1 | SLC16A1 | solute carrier family 16 member 1 | GO:0015728 mevalonate transport;GO:0051780 behavioral response to nutrient;GO:0035879 plasma membrane lactate transport | Transporters:Electrochemical Potential-driven transporters; Disease related genes; Potential drug targets | Cell Junctions;Plasma membrane (Enhanced) | 0 | 0 | 0 | 0 | 1 | |
| TANC2 | TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | GO:0032253 dense core granule localization;GO:0099519 dense core granule cytoskeletal transport;GO:1901950 dense core granule transport | Predicted intracellular proteins; Disease related genes | Cytosol (Approved) | 1 | 0 | 0 | 0 | 0 | |
| TAOK1 | TAOK1 | TAO kinase 1 | GO:0007095 mitotic G2 DNA damage checkpoint;GO:0007026 negative regulation of microtubule depolymerization;GO:0031114 regulation of microtubule depolymerization | Enzymes; Predicted intracellular proteins; Kinases:STE Ser/Thr protein kinases; ENZYME proteins:Transferases | Vesicles (Uncertain) | (M20)PID P38 MKK3 6PATHWAY | 1 | 0 | 0 | 0 | 1 |
| TBL1XR1 | TBL1XR1 | TBL1X receptor 1 | GO:0016575 histone deacetylation;GO:0006476 protein deacetylation;GO:0035601 protein deacylation | Cancer-related genes:Mutated cancer genes; Predicted intracellular proteins; Cancer-related genes:Mutational cancer driver genes; Disease related genes | Nucleoplasm (Approved) | (M223)PID BETA CATENIN NUC PATHWAY | 0 | 1 | 1 | 0 | 0 |
| TECTA | TECTA | tectorin alpha | GO:0007605 sensory perception of sound;GO:0050954 sensory perception of mechanical stimulus;GO:0007160 cell-matrix adhesion | Disease related genes; Predicted secreted proteins | (M3008)NABA ECM GLYCOPROTEINS; (M5884)NABA CORE MATRISOME; (M5889)NABA MATRISOME | 0 | 0 | 0 | 0 | 0 | |
| TLK2 | TLK2 | tousled like kinase 2 | GO:0001672 regulation of chromatin assembly or disassembly;GO:0071480 cellular response to gamma radiation;GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process | Enzymes; Predicted intracellular proteins; Kinases; ENZYME proteins:Transferases | 0 | 1 | 0 | 0 | 0 | ||
| TNRC6B | TNRC6B | trinucleotide repeat containing adaptor 6B | GO:1905616 regulation of miRNA mediated inhibition of translation;GO:1905618 positive regulation of miRNA mediated inhibition of translation;GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | Predicted intracellular proteins | 0 | 0 | 1 | 0 | 0 | ||
| WAC | WAC | WW domain containing adaptor with coiled-coil | GO:0071894 histone H2B conserved C-terminal lysine ubiquitination;GO:0033523 histone H2B ubiquitination;GO:0010390 histone monoubiquitination | Predicted intracellular proteins; Disease related genes | Nucleoplasm (Enhanced) | 0 | 1 | 0 | 0 | 1 |
GO
DisGeNET (gene-disease association)
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