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library(data.table)
fread("/storage11_7T/fuy/TADA-A/CHD/indel_rate/indel+snv_novel_GO.lst")[,-7]
A data.table: 13 × 14
MyListGene SymbolDescriptionBiological Process (GO)Cellular Component (GO)Molecular Function (GO)GO:0008134 transcription factor bindingGO:0009791 post-embryonic developmentGO:0009953 dorsal/ventral pattern formatiGO:0061640 cytoskeleton-dependent cytokinGO:0140285 endosome fissionGO:0010724 regulation of definitive erythGO:0002060 purine nucleobase bindingGO:0032286 central nervous system myelin
<chr><chr><chr><chr><chr><chr><int><int><int><int><int><int><int><int>
MYRF MYRF myelin regulatory factor GO:0032286 central nervous system myelin maintenance;GO:0043217 myelin maintenance;GO:0031643 positive regulation of myelination GO:0005789 endoplasmic reticulum membrane;GO:0098827 endoplasmic reticulum subcompartment;GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane networkGO:0008233 peptidase activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity 00000001
LZTR1 LZTR1 leucine zipper like transcription regulator 1 GO:0046580 negative regulation of Ras protein signal transduction;GO:0051058 negative regulation of small GTPase mediated signal transduction;GO:0046578 regulation of Ras protein signal transduction GO:0031463 Cul3-RING ubiquitin ligase complex;GO:0055038 recycling endosome membrane;GO:0031461 cullin-RING ubiquitin ligase complex GO:0031267 small GTPase binding;GO:0051020 GTPase binding;GO:0019899 enzyme binding 00000000
RBFOX2 RBFOX2 RNA binding fox-1 homolog 2 GO:0010724 regulation of definitive erythrocyte differentiation;GO:0021942 radial glia guided migration of Purkinje cell;GO:0060318 definitive erythrocyte differentiation GO:0005654 nucleoplasm;GO:0031981 nuclear lumen;GO:0005829 cytosol GO:0003714 transcription corepressor activity;GO:0003712 transcription coregulator activity;GO:0003729 mRNA binding 11000100
KIAA0196WASHC5 WASH complex subunit 5 GO:0140285 endosome fission;GO:0040038 polar body extrusion after meiotic divisions;GO:0090306 spindle assembly involved in meiosis GO:0071203 WASH complex;GO:0005769 early endosome;GO:0043025 neuronal cell body GO:0005515 protein binding;GO:0005488 binding 00011000
TMEM258 TMEM258 transmembrane protein 258 GO:0006487 protein N-linked glycosylation;GO:0006486 protein glycosylation;GO:0043413 macromolecule glycosylation GO:0034998 oligosaccharyltransferase I complex;GO:0008250 oligosaccharyltransferase complex;GO:0140534 endoplasmic reticulum protein-containing complex GO:0005515 protein binding;GO:0005488 binding 00000000
PYGL PYGL glycogen phosphorylase L GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process;GO:0046391 5-phosphoribose 1-diphosphate metabolic process;GO:0005980 glycogen catabolic process GO:1904813 ficolin-1-rich granule lumen;GO:0101002 ficolin-1-rich granule;GO:0034774 secretory granule lumen GO:0002060 purine nucleobase binding;GO:0008184 glycogen phosphorylase activity;GO:0102250 linear malto-oligosaccharide phosphorylase activity 10000010
RXRA RXRA retinoid X receptor alpha GO:0035357 peroxisome proliferator activated receptor signaling pathway;GO:0019048 modulation by virus of host process;GO:0048384 retinoic acid receptor signaling pathway GO:0090575 RNA polymerase II transcription regulator complex;GO:0005667 transcription regulator complex;GO:0043235 receptor complex GO:0050692 DNA binding domain binding;GO:0070644 vitamin D response element binding;GO:0044323 retinoic acid-responsive element binding 11000100
DSCAML1 DSCAML1 DS cell adhesion molecule like 1 GO:0070593 dendrite self-avoidance;GO:0001709 cell fate determination;GO:0008038 neuron recognition GO:0030424 axon;GO:0009986 cell surface;GO:0045202 synapse GO:0098632 cell-cell adhesion mediator activity;GO:0098631 cell adhesion mediator activity;GO:0050839 cell adhesion molecule binding 00100000
SMAD2 SMAD2 SMAD family member 2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:0007352 zygotic specification of dorsal/ventral axis;GO:0007182 common-partner SMAD protein phosphorylationGO:0032444 activin responsive factor complex;GO:0071144 heteromeric SMAD protein complex;GO:0071141 SMAD protein complex GO:0034713 type I transforming growth factor beta receptor binding;GO:0070410 co-SMAD binding;GO:0070411 I-SMAD binding 11101000
CIT CIT citron rho-interacting serine/threonine kinaseGO:0035331 negative regulation of hippo signaling;GO:0035330 regulation of hippo signaling;GO:0032467 positive regulation of cytokinesis GO:0005856 cytoskeleton;GO:0005829 cytosol;GO:0043232 intracellular non-membrane-bounded organelle GO:0001223 transcription coactivator binding;GO:0030291 protein serine/threonine kinase inhibitor activity;GO:0097110 scaffold protein binding 10010000
COPB2 COPB2 COPI coat complex subunit beta 2 GO:0006891 intra-Golgi vesicle-mediated transport;GO:1901998 toxin transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum GO:0030126 COPI vesicle coat;GO:0030663 COPI-coated vesicle membrane;GO:0030137 COPI-coated vesicle GO:0005198 structural molecule activity;GO:0005515 protein binding;GO:0005488 binding 00000000
KDM5B KDM5B lysine demethylase 5B GO:0060763 mammary duct terminal end bud growth;GO:0035938 estradiol secretion;GO:2000864 regulation of estradiol secretion GO:0005654 nucleoplasm;GO:0031981 nuclear lumen;GO:0005829 cytosol GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific);GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific);GO:0032453 histone demethylase activity (H3-K4 specific)01000000
RNASEH2CRNASEH2Cribonuclease H2 subunit C GO:0006401 RNA catabolic process;GO:0034655 nucleobase-containing compound catabolic process;GO:0046700 heterocycle catabolic process GO:0032299 ribonuclease H2 complex;GO:0140535 intracellular protein-containing complex;GO:0032991 protein-containing complex GO:0005515 protein binding;GO:0005488 binding 00000000